F2 – Similarity Factor (A Deficiency)

The similarity Factor or F2 is a parameter commonly used to show similarity or equivalence of two dissolution profiles. The F2-value is often calculated using the formula described here (link). The values of F2 range from 0 to 100. Commonly, a value between 50 and 100 is considered to reflect the similarity of two dissolution profiles which implies that the products will have similar in vivo drug release characteristics as well.(please click here for complete post).

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