The prediction of drug concentration-time (C-t) profiles in humans is highly desirable and needed for appropriate development of products and to establish their quality during production. A simple method to predict or estimate the C-t profiles, based on the convolution approach, has been suggested [link].
This article provides an application of the approach for the evaluation of metoprolol tartrate tablet products. Furthermore, it also demonstrates that the approach can be used to predict the C-t profiles for a sub-population as well. please click here for complete post
