The lack of clarity and understanding of the IVIVC concept and practice result in making erroneous claims

The present day confusion regarding IVIVC comes from a poor understanding of the concept and its presentation in the literature. The commonly presented description of the IVIVC concept in literature is the development of the relationships, or lines, between in vitro (dissolution profiles) and in vivo (dissolution or plasma profiles) results, as described earlier (see link).  The confusion comes from both aspects i.e. theoretical, along with its associated mathematical procedures, and the experimental.  Please click here for complete article

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