Should there be drug specific dissolution methods or tests?

It is a common query as to what should be suggested dissolution test conditions for a drug, XYZ, in particular, if the drug XYZ happens to be of low solubility in water. Unfortunately, it is not a correct question, as dissolution tests are mostly conducted for products and not for drugs. Furthermore, even a product does not dictate test conditions, because an analyst likes to determine/establish the property (dissolution) of the product itself, which would require an unbiased method. Therefore, a dissolution method should not be product/drug specific or dependent.

Comments are closed.

Crescent-Shaped Spindle

Now Available
Click here