Presently, only the use of the crescent shape spindle provides true dissolution characteristics of a product

Commonly described dissolution methods are product dependent. Therefore, it is not possible to know whether the observed dissolution characteristics are a reflection of the product (formulation and/or manufacturing) attributes or because of the experimental conditions (apparatus, rpm, medium etc.) employed.

For an appropriate and accurate assessment of dissolution characteristics of a product, the dissolution method must be product independent. The use of crescent shape spindle has been suggested based on this principle, thus provide true dissolution characteristics of a product. Please see the following links, for further discussion:


Comments are closed.

Crescent-Shaped Spindle

Now Available
Click here